![]() ![]() Twenty-eight exams (1%) were excluded from analysis due to duplicate entry, incomplete records, or never-smoker status. LCS exams that had performed since inception of the program (Decemto Janun = 2,227) were reviewed. With the approval of the University of Minnesota Institutional Review Board, demographic characteristics and CT results were extracted from the Lung Cancer Screening Registry. The objective of this study was to determine whether reported rates of incidental findings in a large decentralized LCS program are higher in a university imaging center. Whether reporting incidental findings alters the risk/benefit ratio or the cost-effectiveness of LCS is unknown. In NELSON (Dutch-Belgium Lung Cancer Screening Trial), incidental findings were determined to be mostly without clinical implication ( 7). Higher rates of incidental findings on chest CT are well known, with estimates ranging from 24% in diagnostic CT ( 4, 5) to 86% ( 6) and 94% ( 3) in screening CT. A subsequent analysis did not show a difference in spending attributable to incidental findings ( 2), whereas a real-world study of incidental findings estimated that half of screening reimbursements were due to evaluation of incidental findings ( 3). The NLST (National Lung Screening Trial), a randomized controlled trial, demonstrated a relative reduction in overall and lung cancer mortality ( 1), and left discretion to manage incidental findings (7.5% of exams) to each site. ![]() Lung cancer screening (LCS) with low-dose computed chest tomography (CT) is a preventive service that has been recommended since 2013. ![]()
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